Clinical outcomes after percutaneous coronary intervention in dialysis patients: A comparison of drug-eluting stents and bare-metal stents

Yuya Nakagawa, Yuji Oikawa, Junji Yajima, Funada Ryuichi, Shunsuke Matsuno, Toshiro Inaba, Michinari Nakamura, Ken Ogasawara, Hajime Kirigaya, Kazuyuki Nagashima, Hitoshi Sawada, Tadanori Aizawa

Research output: Contribution to journalArticle

Abstract

Background : It has been reported that the clinical outcomes for dialysis patients treated with percutaneous coronary intervention (PCI) using bare-metal stents (BMS) is unfavorable, however, the efficacy of drug-eluting stents (DES) is unclear. Purpose : To compare the clinical outcomes after PCI in dialysis patients with DES and BMS. Methods and results : Between January 1998 and June 2007, we performed PCI using DES (n = 25) or BMS (n = 72). Among them, 46 patients were followed angiographically (DES : 7, BMS : 39). Mean stent diameter was significantly smaller (2.90 ± 0.29 mm vs. 3.45 ± 0.48 mm, p<0.01) and mean stent length was significantly longer (22.2±5.1 mm vs. 17.9±5.7 mm, p = 0.01) in the DES group. At the follow-up, target lesion revascularization rate (TLR) and overall mortality were similar (16.0% vs. 13.9%, and 28.0% vs. 18.1%, respectively, NS) in both groups. Regarding the angiographic instent restenosis (ISR) pattern, focal ISR (stenosis < 10 mm) tended to be more common in the DES group (75.0% : DES vs. 33.3% : BMS, p = 0.08). Conclusion : In the DES era, PCI has been used for dialysis patients who had more complex lesions compared to those in the BMS era. Although our study could not demonstrate the superiority of DES implantation in dialysis patients concerning restenosis rate, TLR and overall mortality, and angiographical restenosis pattern in DES were all improved compared with BMS implantation.

Original languageEnglish (US)
Pages (from-to)195-199
Number of pages5
JournalJapanese Journal of Interventional Cardiology
Volume24
Issue number3
StatePublished - Jul 21 2009

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All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Keywords

  • BMS
  • DES
  • Hemodialysis

Cite this

Nakagawa, Y., Oikawa, Y., Yajima, J., Ryuichi, F., Matsuno, S., Inaba, T., Nakamura, M., Ogasawara, K., Kirigaya, H., Nagashima, K., Sawada, H., & Aizawa, T. (2009). Clinical outcomes after percutaneous coronary intervention in dialysis patients: A comparison of drug-eluting stents and bare-metal stents. Japanese Journal of Interventional Cardiology, 24(3), 195-199.