Abstract
Abstract Recently, it has been suggested that the clinical staging approach be considered a serious alternative framework for conceptualising mood related psychopathology. The fundamental difference between clinical staging and the now dominant categorical diagnostic framework is that the entire illness trajectory becomes relevant, as opposed to simply the end-stage. The concept of disease trajectory has significant implications for animal models of psychopathology, and particularly for animal models of depression. This article will introduce and discuss the implications of the clinical staging approach for those undertaking research using animal models of mood disturbance.
Original language | English (US) |
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Pages (from-to) | 491-495 |
Number of pages | 5 |
Journal | International Journal of Neuropsychopharmacology |
Volume | 17 |
Issue number | 3 |
DOIs | |
State | Published - Mar 2014 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Pharmacology
- Psychiatry and Mental health
- Pharmacology (medical)
Keywords
- Animal models of depression
- Clinical staging
- Depression
- Mood disorders