COLLAGEN FIBER FORMATION: EFFECT OF GLYCOSAMINOGLYCANS.

Atul K. Garg, Frederick H. Silver

Research output: Contribution to conferencePaperpeer-review

Abstract

Connective tissues are composed of fibrous and nonfibrous components. Collagen and elastic fibers are the fibrous components; other composite macromolecules termed proteoglycans (PG) and glycosaminoglycans (GAG) constitute the nonfibrous components. Previous studies indicated that dextran sulfate, an analog of the sugar component of PG, inhibits type-I collagen fiber formation and decreases fiber organization. Experiments were conducted to study the effect of GAGs on mechanical and physicochemical properties of reconstituted type I collagen fibers for the design of collagen-based implants.

Original languageEnglish (US)
Pages1463-1464
Number of pages2
StatePublished - 1987

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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