Comparison of allograft bone and titanium cages for vertebral body replacement in the thoracolumbar spine: a biomechanical study.

Raul J. Cardenas, Vijayakumar Javalkar, Shashikant Patil, Jorge Gonzalez-Cruz, Alan Ogden, Debi Mukherjee, Anil Nanda

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

When an anterior approach to repair a burst fracture is indicated, several devices can be used to restore spinal stability (eg, bone graft, free-standing titanium cage, and expandable titanium cage). We compare the biomechanical stability and prices of each of these systems. Eight fresh human cadaver T11 through L3 vertebral specimens were harvested and cleaned of soft tissues. T11-T12 and L2-L3 were fixed by screws. The fixed ends were then set in automotive body filler (Bondo). The prepared specimens were tested in the Biaxial Instron tester (8874, Norwood, MA) after a sequence of the following: intact, after the creation of an anterior corpectomy at L1, and after insertion of both of the 2 different titanium cages and the fibular graft. A titanium screw-and-plate anterolateral system was used to secure the construct (VANTAGE, Medtronic Sofamor Danek, Memphis, TN). The conditions of displacement testing were as follows: rotation (+/- 3.5 degrees ), flexion and extension, and left and right bending (+/- 3.5 mm). For each mode of testing, the stiffness was calculated. The stiffness data, when statistically analyzed by repeated-measures analysis of variance (at P = .05 and power > 0.9), indicated no significant differences among these devices. On the basis of this biomechanical study, the stiffness of the fibular graft was similar to that of the other metallic devices in this cadaver model.

Original languageEnglish (US)
Pages (from-to)314-318; discussion 318
JournalNeurosurgery
Volume66
Issue number6 Suppl Operative
StatePublished - Jun 2010
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Comparison of allograft bone and titanium cages for vertebral body replacement in the thoracolumbar spine: a biomechanical study.'. Together they form a unique fingerprint.

Cite this