Complete coverage of the Schizosaccharomyces pombe genome in yeast artificial chromosomes

Elmar Maier; Jörg D. Hoheisel; Linda McCarthy; Richard Mott; Andrei V. Grigoriev; Anthony P. Monaco; Zora Larin; Hans Lehrach

doi:10.1038/ng0792-273

Complete coverage of the Schizosaccharomyces pombe genome in yeast artificial chromosomes

Elmar Maier, Jörg D. Hoheisel, Linda McCarthy, Richard Mott, Andrei V. Grigoriev, Anthony P. Monaco, Zora Larin, Hans Lehrach

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Abstract

The genome of the fission yeast, Schizosaccharomyces pombe, consists of some 14 million base pairs of DNA contained in three chromosomes. On account of its excellent genetics we used it as a test system for a strategy designed to map mammalian chromosomes and genomes. Data obtained from hybridization fingerprinting established an ordered library of 1,248 yeast artificial chromosome clones with an average size of 535 kilobases. The clones fall into three contigs completely representing the three chromosomes of the organism. This work provides a high resolution physical and clone map of the genome, which has been related to available genetic and physical map information.

Original language	English (US)
Pages (from-to)	273-277
Number of pages	5
Journal	Nature genetics
Volume	1
Issue number	4
DOIs	https://doi.org/10.1038/ng0792-273
State	Published - Jul 1992
Externally published	Yes

All Science Journal Classification (ASJC) codes

Genetics

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10.1038/ng0792-273

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title = "Complete coverage of the Schizosaccharomyces pombe genome in yeast artificial chromosomes",

abstract = "The genome of the fission yeast, Schizosaccharomyces pombe, consists of some 14 million base pairs of DNA contained in three chromosomes. On account of its excellent genetics we used it as a test system for a strategy designed to map mammalian chromosomes and genomes. Data obtained from hybridization fingerprinting established an ordered library of 1,248 yeast artificial chromosome clones with an average size of 535 kilobases. The clones fall into three contigs completely representing the three chromosomes of the organism. This work provides a high resolution physical and clone map of the genome, which has been related to available genetic and physical map information.",

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year = "1992",

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AU - Maier, Elmar

AU - Hoheisel, Jörg D.

AU - McCarthy, Linda

AU - Mott, Richard

AU - Grigoriev, Andrei V.

AU - Monaco, Anthony P.

AU - Larin, Zora

AU - Lehrach, Hans

PY - 1992/7

Y1 - 1992/7

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AB - The genome of the fission yeast, Schizosaccharomyces pombe, consists of some 14 million base pairs of DNA contained in three chromosomes. On account of its excellent genetics we used it as a test system for a strategy designed to map mammalian chromosomes and genomes. Data obtained from hybridization fingerprinting established an ordered library of 1,248 yeast artificial chromosome clones with an average size of 535 kilobases. The clones fall into three contigs completely representing the three chromosomes of the organism. This work provides a high resolution physical and clone map of the genome, which has been related to available genetic and physical map information.

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Complete coverage of the Schizosaccharomyces pombe genome in yeast artificial chromosomes

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All Science Journal Classification (ASJC) codes

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