Complicated hypertension related to the abuse of ephedrine and caffeine alkaloids

Jeffrey A. Berman; Arathi Setty; Matthew J. Steiner; Kenneth Kaufman; Christine Skotzko

doi:10.1300/J069v25n03_06

Complicated hypertension related to the abuse of ephedrine and caffeine alkaloids

Jeffrey A. Berman, Arathi Setty, Matthew J. Steiner, Kenneth Kaufman, Christine Skotzko

Robert Wood Johnson Medical School (RWJMS), Psychiatry

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Ephedra containing products (ECPs), which most often contain additional sources of caffeine alkaloids, may be an under-recognized cause of hypertension. ECPs, especially when used in combination or at higher than recommended doses, can cause life-threatening cardiovascular and neurological complications. We present a case of hypertensive encephalopathy with new onset generalized tonic-clonic seizure secondary to concomitant use of two OTC supplements containing a mixture of ephedrine and caffeine alkaloids.

Original language	English (US)
Pages (from-to)	45-48
Number of pages	4
Journal	Journal of Addictive Diseases
Volume	25
Issue number	3
DOIs	https://doi.org/10.1300/J069v25n03_06
State	Published - Aug 31 2006

All Science Journal Classification (ASJC) codes

Medicine (miscellaneous)
Clinical Psychology
Psychiatry and Mental health

Keywords

Caffeine alkaloids
Dietary supplement
Ephedra
Ephedrine
Hypertension
Hypertensive encephalopathy
Over the counter (OTC)
Seizure

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AU - Berman, Jeffrey A.

AU - Setty, Arathi

AU - Steiner, Matthew J.

AU - Kaufman, Kenneth

AU - Skotzko, Christine

PY - 2006/8/31

Y1 - 2006/8/31

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AB - Ephedra containing products (ECPs), which most often contain additional sources of caffeine alkaloids, may be an under-recognized cause of hypertension. ECPs, especially when used in combination or at higher than recommended doses, can cause life-threatening cardiovascular and neurological complications. We present a case of hypertensive encephalopathy with new onset generalized tonic-clonic seizure secondary to concomitant use of two OTC supplements containing a mixture of ephedrine and caffeine alkaloids.

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KW - Dietary supplement

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KW - Hypertension

KW - Hypertensive encephalopathy

KW - Over the counter (OTC)

KW - Seizure

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