Conservative Surgery with Radiation Therapy in Clinical Stage I and II Breast Cancer: Results of a 20-Year Experience

Bruce G. Haffty, Neal B. Goldberg, Marie Rose, Barbara Heil, Diana Fischer, Malcolm Beinfield, Charles Mckhann, Joseph B. Weissberg

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

Conservative surgery and radiation therapy have been increasingly utilized at Yale–New Haven (Conn) Hospital since the 1960s. This analysis represents our experience from 1962 to 1982, with a total of 281 patients having a minimum assessable follow-up of five years and a median follow-up of 7.4 years. Five- and ten-year actuarial survivals were 83% and 67%, respectively. The actuarial breast recurrence-free rate was 91% at five years and 80% at ten years. Of 31 patients having recurrences in the breast alone, the actuarial five-year survival following recurrence was 48%. Twenty-eight (90%) of these 31 recurrences were salvageable with mastectomy or repeated wedge resection. Patients experiencing an early breast recurrence (less than three years) following initial treatment had a poorer prognosis than patients having recurrences later.

Original languageEnglish (US)
Pages (from-to)1266-1270
Number of pages5
JournalArchives of Surgery
Volume124
Issue number11
DOIs
StatePublished - Nov 1989
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery

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