Continuous on-chip micropumping through a microneedle

Jeffrey Zahn, A. A. Deshmukh, A. P. Pisano, D. Liepmann

Research output: Contribution to conferencePaper

33 Scopus citations

Abstract

Microneedles are promising microfabricated devices for minimally invasive drug delivery applications. Microneedles can be integrated into a variety of devices. However, any portable drug delivery device with integrated microneedles will need an equally compact means to deliver the therapeutics. This work presents microneedles integrated with an on-chip MEMS positive displacement micropump for continuous drug delivery applications. The generation and collapse of thermally generated bubbles with flow rectified by directional check valves are used to achieve net pumping. Visualization methods have observed net flow rates of water out of a microneedle at approximately 1.0 nl/s with a pressure of 3.9 kPa. In addition, continuous pumping was achieved for more than 6 hours. The heaters operated for over 18 hours (15,000 cycles) without failing.

Original languageEnglish (US)
Pages503-506
Number of pages4
StatePublished - Jan 1 2001
Externally publishedYes
Event14th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2001) - Interlaken, Switzerland
Duration: Jan 21 2001Jan 25 2001

Other

Other14th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2001)
CountrySwitzerland
CityInterlaken
Period1/21/011/25/01

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All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering
  • Electrical and Electronic Engineering
  • Mechanical Engineering

Cite this

Zahn, J., Deshmukh, A. A., Pisano, A. P., & Liepmann, D. (2001). Continuous on-chip micropumping through a microneedle. 503-506. Paper presented at 14th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2001), Interlaken, Switzerland.