Continuous spike and wave in slow-wave sleep in a patient with rett syndrome and in a patient with lhermitte-duclos syndrome and neurofibromatosis 1

Sushanth Bhat, Xue Ming, Rony Dekermenjian, Sudhansu Chokroverty

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Continuous spike and wave in slow-wave sleep (CSWS) is an electroencephalographic (EEG) pattern characterized by generalized spike-wave discharges occurring for at least 85% of non-rapid eye movement (non-REM) sleep, with marked attenuation during rapid eye movement (REM) sleep. It has been described in a large number of structural and nonstructural neurologic conditions and is associated with epilepsy, behavioral disturbances, and severe neuropsychiatric impairment. We describe continuous spike and wave in slow-wave sleep in 2 patients (one with Rett syndrome and the other with Lhermitte-Duclos syndrome). To our knowledge, continuous spike and wave in slow-wave sleep has not been previously described in these conditions.

Original languageEnglish (US)
Pages (from-to)NP176-NP180
JournalJournal of Child Neurology
Volume29
Issue number12
DOIs
StatePublished - Jan 1 2014

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Keywords

  • CSWS
  • Continuous spike and wave in slow-wave sleep
  • Cowden disease
  • Lhermitte-Duclos syndrome
  • Rett syndrome

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