Cortically projecting nucleus basalis neurons in rat are physiologically heterogeneous

Gary Aston-Jones, Robert Shaver, Timothy Dinan

Research output: Contribution to journalArticle

52 Scopus citations

Abstract

Cortically projecting, putatively cholinergic neurons in the area of globus pallidus (corresponding to nucleus basalis) were identified by antidromic activation from frontal cortex in anesthetized rats. These cells exhibited heterogeneous physiological properties, yielding spontaneous discharge rates of 0-40 Hz, a variety of impulse amplitudes and waveforms, and a wide range of conduction latencies from frontal cortex (1-13 ms). In addition, many cells were found to be antidromically activated from neighboring cortical sites 1-2 mm apart.

Original languageEnglish (US)
Pages (from-to)19-24
Number of pages6
JournalNeuroscience Letters
Volume46
Issue number1
DOIs
StatePublished - Apr 20 1984
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Keywords

  • acetylcholine
  • antidromic activation
  • cholinergic neurons
  • cortical afferents
  • nucleus basalis
  • unit recordings

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