Curcumin inhibits anchorage-independent growth of HT29 human colon cancer cells by targeting epigenetic restoration of the tumor suppressor gene DLEC1

Keyphrases

• Epigenetics 100%
• Lung Cancer 100%
• Tumor Suppressor Gene 100%
• Curcumin 100%
• HT-29 100%
• Human Colon Cancer Cells 100%
• Esophageal Cancer 100%
• Anchorage-independent Growth 100%
• Epigenetic Modification 25%
• Colorectal Cancer Prevention 25%
• Colorectal Cancer 25%
• Knockdown 25%
• Colony Formation 25%
• Epigenetic Regulation 12%
• Lentiviral 12%
• Protein Expression 12%
• Signaling Pathway 12%
• Histone Deacetylases 12%
• Complex Disease 12%
• Cell Proliferation 12%
• Major Components 12%
• Malignancy 12%
• Transcriptional Activity 12%
• Inhibitory Effect 12%
• Short Hairpin RNA (shRNA) 12%
• MRNA Expression 12%
• Bisulfite Sequencing 12%
• Chemopreventive 12%
• Promising Target 12%
• Cell Regulation 12%
• Phytochemicals 12%
• Promoter Methylation 12%
• Demethylation 12%
• DNA Methyltransferase 1 (DNMT1) 12%
• Days of Treatment 12%
• Cell Colony 12%
• CpG Methylation 12%
• Curcuma Longa 12%
• Methylated DNA Immunoprecipitation (MeDIP) 12%
• Methylation-specific Polymerase Chain Reaction 12%
• Inhibitory Role 12%
• Colorectal Adenocarcinoma 12%
• Histone Deacetylase 4 (HDAC4) 12%
• RNA Virus Vector 12%

Biochemistry, Genetics and Molecular Biology

• Cancer Cell 100%
• Epigenetics 100%
• Tumor Suppressor Gene 100%
• Colon 100%
• Anchorage Independent Growth 100%
• Promoter Region 50%
• Methylation 50%
• Colony Formation 50%
• Cell Culture 25%
• Histone Deacetylase 25%
• Cell Proliferation 25%
• Upregulation 25%
• Protein Expression 25%
• Small Hairpin RNA 25%
• Epigenetic Modification 25%
• Genome Sequencing 25%
• Demethylation 25%
• DNA Methyltransferase 25%
• Curcuma 25%
• Phytochemical 25%
• Bisulfite 25%
• Methylated DNA Immunoprecipitation 25%
• HDAC4 25%
• RNA Vector 25%
• Messenger RNA 25%
• Polymerase Chain Reaction 25%