Cutaneous manifestations of systemic cryptococcosis in immunosupressed patients

Thomas Isabelle, R. H K Eng, Robert Schwartz

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Since its discovery 100 years ago, the encapsulated yeast Cryptococcus neoformans has been implicated in systemic infections of many immunocompromised patients and has been a leading cause of morbidity and mortality in AIDS patients. Clinical symptoms are often initially subtle or lacking. Cutaneous involvement often carries a dismal prognosis as it is usually a sign of dissemination. However, lesions may develop before any systemic or constitutional symptomatology, and despite their non specific appearance, are easily accessible for scrapings, biopsies and cultures. A high index of suspicion is of utmost importance in high risk individuals to avoid delaying the diagnosis and treatment.

Original languageEnglish (US)
Pages (from-to)259-266
Number of pages8
JournalJournal of Medicine
Volume32
Issue number5-6
StatePublished - Dec 1 2001
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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