Cutaneous signs of selected systemic diseases

N. I. Kihiczak, C. B. Leevy, M. M. Krysicki, C. K. Janniger, I. Schneider, D. L. Shriner, W. C. Lambert, R. A. Schwartz

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


In this work we will discuss three cutaneous markers of systemic disease. Acanthosis nigricans is the most widely known in this category. Cutaneous angiokeratomas are usually associated with enzyme defect disorders, such as Fabry's disease, and are linked in this work as a reactive pattern in hepatorenal failure. Mast cell disease may occur in a number of forms, often with systemic involvement.

Original languageEnglish (US)
Pages (from-to)3-12
Number of pages10
JournalJournal of medicine
Issue number1-2
StatePublished - 1999

All Science Journal Classification (ASJC) codes

  • Medicine(all)


  • Acanthosis nigricans
  • Angiokeratoma
  • Cutaneous markers of systemic disease
  • Mastocytosis


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