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Cytotoxic properties of leaf essential oil and components from indigenous cinnamon (Cinnamomum osmophloeum Kaneh)

  • Tzou Chi Huang
  • , Chi Tang Ho
  • , Hui Yin Fu
  • , Min Hsiung Pan

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The essential oils from leaves of three Cinnamomum osmophloeum clones (A, B and C) and their major chemical constituents were investigated. GC and GC-MS analyses showed that Cinnamomum osmophloeum clones A, B and C contain trns-cinnamaldehyde (90.6%), eugenol (91.3%) and linalool (83.7%), respectively, as the major component. The inhibitory effects of the essential oils on the growth of human leukemia cell lines U937 and K562 Hep-1, in vitro were investigated. A strong cell proliferation inhibition activity for Cinnamomum osmophloeum clone A was observed for cell lines K562, whereas Cinnamomum osmophloeum clone B and Cinnamomum osmophloeum clone C gave comparatively low inhibition. This trend paralleled the cytotoxic properties of authentic trans-cinnaldehyde, eugenol and linalool, respectively.

Original languageEnglish (US)
Title of host publicationHerbs
Subtitle of host publicationChallenges in Chemistry and Biology
EditorsMingfu Wang, Chi-Tang Ho, Shengmin Sang, Lucy Sun Hwang
Pages299-313
Number of pages15
StatePublished - 2006

Publication series

NameACS Symposium Series
Volume925
ISSN (Print)0097-6156

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • General Chemical Engineering

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