Daywake, an Anti-siesta Gene Linked to a Splicing-Based Thermostat from an Adjoining Clock Gene

Yong Yang, Isaac Edery

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Yong and Edery identify an anti-siesta gene in Drosophila, hereinafter termed daywake, that is regulated in an unprecedented manner by splicing of the cold-enhanced dmpi8 intron from the reverse-oriented and slightly overlapping period clock gene. The dmpi8-dyw unit stimulates midday activity on days that carry less risks from heat exposure.

Original languageEnglish (US)
Pages (from-to)1728-1734.e4
JournalCurrent Biology
Volume29
Issue number10
DOIs
StatePublished - May 20 2019

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Keywords

  • 0.9 gene
  • Daywake
  • Drosophila
  • dmpi8 intron
  • juvenile hormone-binding protein
  • midday siesta
  • period clock gene
  • pre-mRNA splicing
  • sleep-wake behavior

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