Decreased T-lymphocytes in patients with mammary cancer

Steven Keller, H. L. Ioachim, T. Pearse, D. M. Siletti

Research output: Contribution to journalArticle

44 Scopus citations

Abstract

The levels of thymus derived lymphocytes (T cells) in samples of peripheral blood from 47 patients with carcinoma of the breast, 36 patients with benign mammary lesions, and 33 matched normal controls were determined. Results were analyzed with 3 statistical tests. It was found that the mean percentages of T lymphocytes differed significantly among the 3 groups of patients (p<0.001). The mean percentages of rosette forming lymphocytes were 72.8 for the normal group, 60.6 for patients with benign mammary lesions, and 45.1 for the patients with carcinoma. The finding of lower levels of T lymphocytes in the peripheral blood of individuals with mammary cancer is of particular significance since all the patients in this study were otherwise in apparently good general health and undergoing no treatment.

Original languageEnglish (US)
Pages (from-to)445-449
Number of pages5
JournalAmerican Journal of Clinical Pathology
Volume65
Issue number4
DOIs
StatePublished - Jan 1 1976
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

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