Demographics and survival trends of sinonasal adenocarcinoma from 1973 to 2009

Christine M. D'Aguillo, Vivek V. Kanumuri, Mohemmed N. Khan, Saurin Sanghvi, Neal R. Patel, Soly Baredes, Jean Anderson Eloy

Research output: Contribution to journalArticle

17 Scopus citations


Background: The purpose of this work was to study the demographics and survival of patients diagnosed with sinonasal adenocarcinoma (SNAC) within the time period of 1973 to 2009 using the Surveillance, Epidemiology, and End Result (SEER) database. Methods: A retrospective cohort study using the U.S. National Cancer Institute's SEER registry was performed to study the demographics and survival for SNAC from 1973 to 2009. Analysis was conducted based on race, gender, and stage. Results: In total, 1270 cases of SNAC were analyzed for demographics and survival. Males accounted for 51.6% of cases, while females accounted for 48.4% of cases, amounting to a male to female ratio of 1.06:1.00. Disease specific survival at 5, 10, 15, and 20 years was 65.2%, 50.9%, 40.9%, and 36.5%, respectively. When analyzed by gender, females had higher survival than males, although this difference was not statistically significant. When analyzed by race, the category of other, which encompasses American Indian, Asian, Hispanic, and unknown or unspecified race, was shown to have the best survival, followed by whites and blacks, respectively. Conclusion: SNAC is a rare tumor classically associated with occupational exposure and carries a variable prognosis. This is the first dedicated large-scale, retrospective analysis of a North American SNAC population. SNAC appears to affect both males and females equally and predominantly affects whites.

Original languageEnglish (US)
Pages (from-to)771-776
Number of pages6
JournalInternational Forum of Allergy and Rhinology
Issue number9
StatePublished - Jan 1 2014


All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Otorhinolaryngology


  • Adenocarcinoma
  • Epidemiology
  • Ethmoid cancer
  • Gender
  • Long-term survival
  • Nasal cancer
  • Occupational exposure
  • Paranasal cancer
  • Sinonasal cancer
  • Surveillance, Epidemiology, and End Result (SEER) database

Cite this

D'Aguillo, C. M., Kanumuri, V. V., Khan, M. N., Sanghvi, S., Patel, N. R., Baredes, S., & Eloy, J. A. (2014). Demographics and survival trends of sinonasal adenocarcinoma from 1973 to 2009. International Forum of Allergy and Rhinology, 4(9), 771-776.