Dermatomyositis: An association of gingival telangiectases and anti Jo-1 antibody in the adult

Lyubomir A. Dourmishev, Assen L. Dourmishev, Robert A. Schwartz

Research output: Contribution to journalArticle

7 Scopus citations


Background: The presence of gingival telangiectases is an unusual clinical finding in adults with dermatomyositis (DM). Patients with aminoacyl-tRNA synthetase autoantibodies express one or more of the following features: myositis, interstitial lung disease, "mechanic's hands," and capillary abnormalities (facial telangiectases and Raynaud's phenomenon). Case report: A 45-year-old woman with a classic form of DM of ten years' duration was evaluated. Clinical investigation revealed periorbital edema and violaceous erythema of the eyelids, Gottron's papules of the fingers, Gottron's sign on the elbows and malleoli, a plantar fissured, hyperkeratotic, and scaling eruption ("calloused feet"), ragged cuticles with dilated nail-fold telangiectasia, and gingival telangiectases. The patient fulfilled Bohan and Peter's criteria for the clinical, histological, EMG, and biochemical diagnosis of DM. Elevated titers of ANA (1:320) with a speckled pattern and anti Jo-1 antibodies were found in her sera by ELISA and Western blot. Conclusion: The recognition of subsets within the spectrum of DM characterized by certain clinical and serological features may be important. Because facial telangiectases are a recognized finding in this subset of patients, we suggest that gingival telangiectases might be a marker for the antisynthetase syndrome.

Original languageEnglish (US)
Pages (from-to)67-72
Number of pages6
JournalActa Dermatovenerologica Alpina, Pannonica et Adriatica
Issue number2
StatePublished - Jun 1 2007

All Science Journal Classification (ASJC) codes

  • Dermatology
  • Infectious Diseases


  • Antisynthetase syndrome
  • Dermatomyositis
  • Gingival telangiectases

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