Accurate and rapid assessment of Candida auris antifungal drug resistance is crucial for effective infection prevention and control actions, as well as for patient management. Here, performance of a molecular diagnostic platform, enabling rapid identification of FKS1 and ERG11 mutations conferring echinocandin and azole resistance, respectively, was evaluated on a panel of clinical skin swabs. Gene sequencing and antifungal susceptibility testing were used as the gold standard. All swabs were correctly categorized as harboring wild-type or mutant C. auris.
All Science Journal Classification (ASJC) codes
- Pharmacology (medical)
- Infectious Diseases
- Antifungal resistance
- Antifungal susceptibility testing
- Candida auris
- Drug resistance mechanisms