A convenient procedure for the extraction and determination of three organophosphate insecticides, their active oxygen analogs, and their inactive metabolites in biological tissues is described. The utility of this technique is demonstrated by measurement of the in vitro biotransformation of both parathion and chlorpyrifos by mouse hepatic microsomes.
All Science Journal Classification (ASJC) codes
- Analytical Chemistry
- Clinical Biochemistry
- Organic Chemistry
- High-performance liquid chromatography
- Organophosphate pesticide metabolites
- Organophosphate pesticides