TY - JOUR
T1 - Development of Isolated Hepatic Perfusion for Patients Who Have Unresectable Hepatic Malignancies
AU - Jones, Adriana
AU - Alexander, H. Richard
PY - 2008/10
Y1 - 2008/10
N2 - Isolated hepatic perfusion (IHP) has a role in the treatment of colorectal carcinoma, ocular melanoma, and neuroendocrine tumor liver metastases. Outcomes data with IHP have improved with better patient selection, adoption of standard operative techniques, use of appropriate types and doses of chemotherapeutics, and careful measures of efficacy and survival. The percutaneous approach to IHP, the treatment of additional tumor types (eg, unresectable hepatocellular carcinoma, gastrointestinal sarcoma, occult primaries), the use of other agents within the IHP circuit, and gene therapy all deserve additional attention.
AB - Isolated hepatic perfusion (IHP) has a role in the treatment of colorectal carcinoma, ocular melanoma, and neuroendocrine tumor liver metastases. Outcomes data with IHP have improved with better patient selection, adoption of standard operative techniques, use of appropriate types and doses of chemotherapeutics, and careful measures of efficacy and survival. The percutaneous approach to IHP, the treatment of additional tumor types (eg, unresectable hepatocellular carcinoma, gastrointestinal sarcoma, occult primaries), the use of other agents within the IHP circuit, and gene therapy all deserve additional attention.
UR - http://www.scopus.com/inward/record.url?scp=49649097887&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=49649097887&partnerID=8YFLogxK
U2 - 10.1016/j.soc.2008.04.011
DO - 10.1016/j.soc.2008.04.011
M3 - Review article
C2 - 18722923
AN - SCOPUS:49649097887
SN - 1055-3207
VL - 17
SP - 857
EP - 876
JO - Surgical Oncology Clinics of North America
JF - Surgical Oncology Clinics of North America
IS - 4
ER -