Dipping into the cytosol to broaden the MHC class II peptide repertoire

Lisa K. Denzin; Derek B. Sant'Angelo

doi:10.1016/j.immuni.2005.05.003

Dipping into the cytosol to broaden the MHC class II peptide repertoire

Lisa K. Denzin, Derek B. Sant'Angelo

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

A new study by Zhou et al. (2005) in this issue of Immunity explores how cytoplasmic autoantigens gain access to the MHC class II antigen-processing pathway. Their experiments show that hsc70 and Lamp-2a mediate antigen transport into endosomal compartments for presentation by MHC class II.

Original language	English (US)
Pages (from-to)	536-537
Number of pages	2
Journal	Immunity
Volume	22
Issue number	5
DOIs	https://doi.org/10.1016/j.immuni.2005.05.003
State	Published - May 2005
Externally published	Yes

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Immunology
Infectious Diseases

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10.1016/j.immuni.2005.05.003

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title = "Dipping into the cytosol to broaden the MHC class II peptide repertoire",

abstract = "A new study by Zhou et al. (2005) in this issue of Immunity explores how cytoplasmic autoantigens gain access to the MHC class II antigen-processing pathway. Their experiments show that hsc70 and Lamp-2a mediate antigen transport into endosomal compartments for presentation by MHC class II.",

author = "Denzin, {Lisa K.} and Sant'Angelo, {Derek B.}",

year = "2005",

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doi = "10.1016/j.immuni.2005.05.003",

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journal = "Immunity",

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AU - Denzin, Lisa K.

AU - Sant'Angelo, Derek B.

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AB - A new study by Zhou et al. (2005) in this issue of Immunity explores how cytoplasmic autoantigens gain access to the MHC class II antigen-processing pathway. Their experiments show that hsc70 and Lamp-2a mediate antigen transport into endosomal compartments for presentation by MHC class II.

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DO - 10.1016/j.immuni.2005.05.003

M3 - Short survey

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JO - Immunity

JF - Immunity

SN - 1074-7613

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ER -

Dipping into the cytosol to broaden the MHC class II peptide repertoire

Abstract

All Science Journal Classification (ASJC) codes

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