Dipping into the cytosol to broaden the MHC class II peptide repertoire

Lisa K. Denzin; Derek B. Sant'Angelo

doi:10.1016/j.immuni.2005.05.003

Dipping into the cytosol to broaden the MHC class II peptide repertoire

Lisa K. Denzin, Derek B. Sant'Angelo

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

A new study by Zhou et al. (2005) in this issue of Immunity explores how cytoplasmic autoantigens gain access to the MHC class II antigen-processing pathway. Their experiments show that hsc70 and Lamp-2a mediate antigen transport into endosomal compartments for presentation by MHC class II.

Original language	English (US)
Pages (from-to)	536-537
Number of pages	2
Journal	Immunity
Volume	22
Issue number	5
DOIs	https://doi.org/10.1016/j.immuni.2005.05.003
State	Published - May 2005

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Immunology
Infectious Diseases

Access to Document

10.1016/j.immuni.2005.05.003

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title = "Dipping into the cytosol to broaden the MHC class II peptide repertoire",

abstract = "A new study by Zhou et al. (2005) in this issue of Immunity explores how cytoplasmic autoantigens gain access to the MHC class II antigen-processing pathway. Their experiments show that hsc70 and Lamp-2a mediate antigen transport into endosomal compartments for presentation by MHC class II.",

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