Dipping into the cytosol to broaden the MHC class II peptide repertoire

Research output: Contribution to journalShort surveypeer-review

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Abstract

A new study by Zhou et al. (2005) in this issue of Immunity explores how cytoplasmic autoantigens gain access to the MHC class II antigen-processing pathway. Their experiments show that hsc70 and Lamp-2a mediate antigen transport into endosomal compartments for presentation by MHC class II.

Original languageEnglish (US)
Pages (from-to)536-537
Number of pages2
JournalImmunity
Volume22
Issue number5
DOIs
StatePublished - May 2005

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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