DNA-crowded enzyme complexes with enhanced activities and stabilities

John Collins, Ting Zhang, Sung Won Oh, Robert Maloney, Jinglin Fu

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

We present a robust and simple method to prepare DNA-crowded enzyme complexes by directly assembling long DNA duplexes on the enzyme surface. DNA-crowded enzyme complexes show boosted substrate turnover numbers, and increased stabilities against various storage conditions. They could be potentially scaled up for applications in biomaterials and biotechnology.

Original languageEnglish (US)
Pages (from-to)13059-13062
Number of pages4
JournalChemical Communications
Volume53
Issue number97
DOIs
Publication statusPublished - Jan 1 2017

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All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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