DNA polymerases of human tonsil and chicken bursa: Absence of a distinct B cell specific terminal deoxynucleotidyl transferase

Mukund J. Modak, Harshida Bhatt, Scott Seidner, Edwin C. Hahn, Sudhir Gupta, Robert A. Good

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

The extracts obtained from chicken bursas and human tonsils, both of which are known to contain predominantly B lymphocyte precursor cells, were examined for the presence of putative B cell specific terminal deoxynucleotidyl transferase (B-TdT). Neither of the two types of tissue extracts revealed the presence of specific TdT, although the presence of DNA polymerase α, β, and γ could be easily demonstrated.

Original languageEnglish (US)
Pages (from-to)266-273
Number of pages8
JournalBiochemical and Biophysical Research Communications
Volume83
Issue number1
DOIs
StatePublished - Jul 14 1978
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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