DNA uptake during bacterial transformation

Inês Chen, David Dubnau

Research output: Contribution to journalReview article

392 Citations (Scopus)

Abstract

Naturally competent bacteria are able to take up exogenous DNA and undergo genetic transformation. The transport of DNA from the extracellular milieu into the cytoplasm is a complex process, and requires proteins that are related to those involved in the assembly of type IV pili and type II secretion systems, as well as a DNA translocase complex at the cytoplasmic membrane. Here, we will review the current knowledge of DNA transport during transformation.

Original languageEnglish (US)
Pages (from-to)241-249
Number of pages9
JournalNature Reviews Microbiology
Volume2
Issue number3
DOIs
StatePublished - Mar 1 2004

Fingerprint

Bacterial Transformation
DNA
Genetic Transformation
Cytoplasm
Cell Membrane
Bacteria
Proteins

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology and Microbiology(all)
  • Infectious Diseases

Cite this

Chen, Inês ; Dubnau, David. / DNA uptake during bacterial transformation. In: Nature Reviews Microbiology. 2004 ; Vol. 2, No. 3. pp. 241-249.
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DNA uptake during bacterial transformation. / Chen, Inês; Dubnau, David.

In: Nature Reviews Microbiology, Vol. 2, No. 3, 01.03.2004, p. 241-249.

Research output: Contribution to journalReview article

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