Does FASing Out New Fat in the Hypothalamus Make You Slim?

Christoph Buettner

doi:10.1016/j.cmet.2007.09.008

Does FASing Out New Fat in the Hypothalamus Make You Slim?

Christoph Buettner

Research output: Contribution to journal › Short survey › peer-review

3 Scopus citations

Abstract

Fatty acid synthase (FAS) is a key enzyme for lipogenesis. A recent study (Chakravarthy et al., 2007) shows that the targeted deletion of FAS in hypothalamic neurons produces hypophagic, lean mice and suggests that PPARα signaling is an important mediator of the effects of FAS on energy homeostasis.

Original language	English (US)
Pages (from-to)	249-251
Number of pages	3
Journal	Cell Metabolism
Volume	6
Issue number	4
DOIs	https://doi.org/10.1016/j.cmet.2007.09.008
State	Published - Oct 3 2007
Externally published	Yes

All Science Journal Classification (ASJC) codes

Physiology
Molecular Biology
Cell Biology

Access to Document

10.1016/j.cmet.2007.09.008

Cite this

@article{e384b39fba694e6aba1ab102d652bab1,

title = "Does FASing Out New Fat in the Hypothalamus Make You Slim?",

abstract = "Fatty acid synthase (FAS) is a key enzyme for lipogenesis. A recent study (Chakravarthy et al., 2007) shows that the targeted deletion of FAS in hypothalamic neurons produces hypophagic, lean mice and suggests that PPARα signaling is an important mediator of the effects of FAS on energy homeostasis.",

author = "Christoph Buettner",

year = "2007",

month = oct,

day = "3",

doi = "10.1016/j.cmet.2007.09.008",

language = "English (US)",

volume = "6",

pages = "249--251",

journal = "Cell Metabolism",

issn = "1550-4131",