Dorello's canal and Gruber's ligament: Historical perspective

Sudheer Ambekar, Ashish Sonig, Anil Nanda

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Wenzel Leopold Gruber and Primo Dorello were great anatomists and researchers during the 19th and 20th centuries. Their contributions to neuroanatomy-namely the Gruber's (petrosphenoidal) ligament and Dorello's canal, respectively-have come to be important structures in various approaches through the middle fossa. These structures have also helped provide us with an understanding of the mechanism of sixth nerve paresis in various pathological conditions, such as raised intracranial pressure and Gradenigo syndrome. Their numerous publications have stood as a reference to anatomical researchers. Gruber's description of internal mesogastric hernia and the Meckel-Gruber anastomosis are also widely known in medical literature. The following article is an attempt to reflect upon the life and works of Gruber and Dorello and the importance of their research.

Original languageEnglish (US)
Pages (from-to)430-433
Number of pages4
JournalJournal of Neurological Surgery, Part B: Skull Base
Issue number6
StatePublished - Dec 2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Clinical Neurology


  • Abducens nerve
  • Dorello
  • Gruber
  • Petrosphenoidal ligament


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