TY - JOUR
T1 - Dorsal, an embryonic polarity gene in drosophila, is homologous to the vertebrate proto-oncogene, c-rel
AU - Steward, Ruth
PY - 1987
Y1 - 1987
N2 - The Drosophila. gene, dorsal, is a maternal effect locus that is essential for the establishment of dorsal-ventral polarity in the developing embryo. The dorsal protein was predicted from the complementary DNA sequence; it is almost 50 percent identical, over an extensive region, to the protein encoded by the avian oncogene v-rel, its cellular homolog, c-rel, and a human c-rel fragment. The oncogene v-rel is highly oncogenic in avian lymphoid, spleen, and bone marrow cells.
AB - The Drosophila. gene, dorsal, is a maternal effect locus that is essential for the establishment of dorsal-ventral polarity in the developing embryo. The dorsal protein was predicted from the complementary DNA sequence; it is almost 50 percent identical, over an extensive region, to the protein encoded by the avian oncogene v-rel, its cellular homolog, c-rel, and a human c-rel fragment. The oncogene v-rel is highly oncogenic in avian lymphoid, spleen, and bone marrow cells.
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U2 - 10.1126/science.3118464
DO - 10.1126/science.3118464
M3 - Article
C2 - 3118464
AN - SCOPUS:0023619362
VL - 238
SP - 692
EP - 694
JO - Science
JF - Science
SN - 0036-8075
IS - 4827
ER -