Dynamic assessment of titanium surface oxides following mechanical damage reveals only partial passivation under inflammatory conditions

Georgios A. Kotsakis; Li Xie; Danyal A. Siddiqui; Diane Daubert; Daniel J. Graham; Francisco Javier Gil

doi:10.1038/s41529-024-00514-1

Dynamic assessment of titanium surface oxides following mechanical damage reveals only partial passivation under inflammatory conditions

Georgios A. Kotsakis, Li Xie, Danyal A. Siddiqui, Diane Daubert, Daniel J. Graham, Francisco Javier Gil

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Motivated by clinical problems of titanium implant degradation, we developed a workflow that enabled assessment of surface oxide dynamics as a function of clinical interventions and inflammation conditions. We found that mechanical damage led to decrease of stoichiometric TiO₂ ratio in the passivation oxide film and further resulted in accelerated degradation under inflammatory anaerobic conditions. This method can be employed for the assessment of surface oxides to monitor implant safety.

Original language	English (US)
Article number	98
Journal	npj Materials Degradation
Volume	8
Issue number	1
DOIs	https://doi.org/10.1038/s41529-024-00514-1
State	Published - Dec 2024
Externally published	Yes

All Science Journal Classification (ASJC) codes

Ceramics and Composites
Chemistry (miscellaneous)
Materials Science (miscellaneous)
Materials Chemistry

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10.1038/s41529-024-00514-1

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title = "Dynamic assessment of titanium surface oxides following mechanical damage reveals only partial passivation under inflammatory conditions",

abstract = "Motivated by clinical problems of titanium implant degradation, we developed a workflow that enabled assessment of surface oxide dynamics as a function of clinical interventions and inflammation conditions. We found that mechanical damage led to decrease of stoichiometric TiO2 ratio in the passivation oxide film and further resulted in accelerated degradation under inflammatory anaerobic conditions. This method can be employed for the assessment of surface oxides to monitor implant safety.",

author = "Kotsakis, {Georgios A.} and Li Xie and Siddiqui, {Danyal A.} and Diane Daubert and Graham, {Daniel J.} and Gil, {Francisco Javier}",

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AU - Kotsakis, Georgios A.

AU - Xie, Li

AU - Siddiqui, Danyal A.

AU - Daubert, Diane

AU - Graham, Daniel J.

AU - Gil, Francisco Javier

PY - 2024/12

Y1 - 2024/12

N2 - Motivated by clinical problems of titanium implant degradation, we developed a workflow that enabled assessment of surface oxide dynamics as a function of clinical interventions and inflammation conditions. We found that mechanical damage led to decrease of stoichiometric TiO2 ratio in the passivation oxide film and further resulted in accelerated degradation under inflammatory anaerobic conditions. This method can be employed for the assessment of surface oxides to monitor implant safety.

AB - Motivated by clinical problems of titanium implant degradation, we developed a workflow that enabled assessment of surface oxide dynamics as a function of clinical interventions and inflammation conditions. We found that mechanical damage led to decrease of stoichiometric TiO2 ratio in the passivation oxide film and further resulted in accelerated degradation under inflammatory anaerobic conditions. This method can be employed for the assessment of surface oxides to monitor implant safety.

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Dynamic assessment of titanium surface oxides following mechanical damage reveals only partial passivation under inflammatory conditions

Abstract

All Science Journal Classification (ASJC) codes

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