EEG monitoring during therapeutic hypothermia in neonates, children, and adults

Nicholas S. Abend, Ram Mani, Tammy N. Tschuda, Tae Chang, Alexis A. Topjian, Maureen Donnelly, Denise LaFalce, Margaret C. Krauss, Sarah E. Schmitt, Joshua M. Levine

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Therapeutic hypothermia is being utilized as a neuroprotective strategy in neonates, children, and adults. The most common indications are hypoxic ischemic encephalopathy in neonates and post cardiac arrest in adults. Electroencephalographic monitoring use is increasing in critical care units, and is sometimes a component of therapeutic hypothermia clinical pathways. Monitoring may detect nonconvulsive seizures or non-convulsive status epilepticus, and it may provide prognostic information. We review data regarding indications for therapeutic hypothermia and electroencephalographic monitoring in neonatal, pediatric, and adult critical care units, and discuss technical aspects related to such monitoring.

Original languageEnglish (US)
Pages (from-to)141-164
Number of pages24
JournalNeurodiagnostic Journal
Issue number3
StatePublished - 2011

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Medical Laboratory Technology


  • Cardiac arrest
  • EEG
  • Neonatal hypoxic ischemic encephalopathy
  • Non-convulsive seizures
  • Seizures
  • Therapeutic hypothermia
  • Traumatic brain injury


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