Effects of clenbuterol on horses

S. D. Drake, L. E. Hansen, C. Harris, W. C. Lewis, E. Miller, B. Moranville, M. Blyzka, W. G. Bergen, K. H. McKeever, G. J. Hausman, M. V. Dodson

Research output: Contribution to journalReview article

Abstract

Clenbuterol was intended as a treatment for respiratory diseases in horses, but has been used in multiple species, including humans, for its repartitioning of fat to lean effects (free fatty acids are released from adipose tissue to be used by tissues of higher priority). In the horse industry clenbuterol application is restricted to the treatment of chronic obstructive pulmonary disease and reactive airway disease (heaves). Negative effects of clenbuterol exposure include a decrease in maximum oxygen intake and increased muscle fatigue upon exercise. As a result of these and other negative effects, clenbuterol remains strictly controlled by the US Food and Drug Administration.

Original languageEnglish (US)
Pages (from-to)181-187
Number of pages7
JournalComparative Exercise Physiology
Volume9
Issue number3-4
DOIs
StatePublished - Jan 1 2013

Fingerprint

Clenbuterol
clenbuterol
Horses
horses
Pulmonary diseases
respiratory tract diseases
muscle fatigue
Horse Diseases
Tissue
Muscle Fatigue
United States Food and Drug Administration
Nonesterified Fatty Acids
Chronic Obstructive Pulmonary Disease
adipose tissue
Muscle
free fatty acids
Adipose Tissue
Industry
exercise
Fats

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Physiology
  • Orthopedics and Sports Medicine
  • veterinary (miscalleneous)
  • Physiology (medical)

Keywords

  • Bronchodilator
  • Equine
  • Repartitioning
  • β-adrenergic agonist

Cite this

Drake, S. D., Hansen, L. E., Harris, C., Lewis, W. C., Miller, E., Moranville, B., ... Dodson, M. V. (2013). Effects of clenbuterol on horses. Comparative Exercise Physiology, 9(3-4), 181-187. https://doi.org/10.3920/CEP13022
Drake, S. D. ; Hansen, L. E. ; Harris, C. ; Lewis, W. C. ; Miller, E. ; Moranville, B. ; Blyzka, M. ; Bergen, W. G. ; McKeever, K. H. ; Hausman, G. J. ; Dodson, M. V. / Effects of clenbuterol on horses. In: Comparative Exercise Physiology. 2013 ; Vol. 9, No. 3-4. pp. 181-187.
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Drake, SD, Hansen, LE, Harris, C, Lewis, WC, Miller, E, Moranville, B, Blyzka, M, Bergen, WG, McKeever, KH, Hausman, GJ & Dodson, MV 2013, 'Effects of clenbuterol on horses', Comparative Exercise Physiology, vol. 9, no. 3-4, pp. 181-187. https://doi.org/10.3920/CEP13022

Effects of clenbuterol on horses. / Drake, S. D.; Hansen, L. E.; Harris, C.; Lewis, W. C.; Miller, E.; Moranville, B.; Blyzka, M.; Bergen, W. G.; McKeever, K. H.; Hausman, G. J.; Dodson, M. V.

In: Comparative Exercise Physiology, Vol. 9, No. 3-4, 01.01.2013, p. 181-187.

Research output: Contribution to journalReview article

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T1 - Effects of clenbuterol on horses

AU - Drake, S. D.

AU - Hansen, L. E.

AU - Harris, C.

AU - Lewis, W. C.

AU - Miller, E.

AU - Moranville, B.

AU - Blyzka, M.

AU - Bergen, W. G.

AU - McKeever, K. H.

AU - Hausman, G. J.

AU - Dodson, M. V.

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AB - Clenbuterol was intended as a treatment for respiratory diseases in horses, but has been used in multiple species, including humans, for its repartitioning of fat to lean effects (free fatty acids are released from adipose tissue to be used by tissues of higher priority). In the horse industry clenbuterol application is restricted to the treatment of chronic obstructive pulmonary disease and reactive airway disease (heaves). Negative effects of clenbuterol exposure include a decrease in maximum oxygen intake and increased muscle fatigue upon exercise. As a result of these and other negative effects, clenbuterol remains strictly controlled by the US Food and Drug Administration.

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KW - Equine

KW - Repartitioning

KW - β-adrenergic agonist

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Drake SD, Hansen LE, Harris C, Lewis WC, Miller E, Moranville B et al. Effects of clenbuterol on horses. Comparative Exercise Physiology. 2013 Jan 1;9(3-4):181-187. https://doi.org/10.3920/CEP13022