An experiment was performed in order to determine the role of the medial aspect of the prefrontal cortex in the regulation of aggressive behavior in the cat. The results of this study demonstrated that electrical stimulation of the medial prefrontal cortex suppressed quiet biting attack, affective display elicited from electrical stimulation of the hypothalamus, and spontaneously elicited quiet biting attack. In contrast, stimulation of the prefrontal cortex did not measurably affect flight responses elicited from stimulation of the hypothalamus. The results of anatomical studies in the cat have suggested that inhibition of aggression is mediated indirectly upon the hypothalamus via the mediodorsal thalamic nucleus.
All Science Journal Classification (ASJC) codes
- Molecular Biology
- Clinical Neurology
- Developmental Biology