Effects of sample arm motion in endoscopic polarization-sensitive optical coherence tomography

Mark C. Pierce, Milen Shishkov, B. Hyle Park, Nader A. Nassif, Brett E. Bouma, Guillermo J. Tearney, Johannes F. De Boer

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Motion of the sample arm fiber in optical coherence tomography (OCT) systems can dynamically alter the polarization state of light incident on tissue during imaging, with consequences for both conventional and polarization-sensitive (PS-)OCT. Endoscopic OCT is particularly susceptible to polarization-related effects, since in most cases, the transverse scanning mechanism involves motion of the sample arm optical fiber to create an image. We investigated the effects of a scanning sample arm fiber on the polarization state of light in an OCT system, and demonstrate that by referencing the state backscattered from within a sample to the measured state at the surface, changes in polarization state due to sample fiber motion can be isolated. The technique is demonstrated by high-speed PS-OCT imaging at 1 frame per second, with both linear and rotary scanning fiberoptic probes. Measurements were made on a calibrated wave plate, and endoscopic PS-OCT images of ex-vivo human tissues are also presented, allowing comparison with features in histologic sections.

Original languageEnglish (US)
Pages (from-to)5739-5749
Number of pages11
JournalOptics Express
Issue number15
StatePublished - Jul 25 2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics


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