Abstract
Confocal laser endomicroscopy (CLE) is an in vivo imaging modality that allows optical biopsies to be obtained during the evaluation of biliary strictures. Compared with pathology, CLE has higher sensitivity and accuracy for the evaluation of indeterminate biliary strictures. CLE has the ability to increase the diagnostic yield of endoscopic retrograde cholangiopancreatography (ERCP), reducing the need for repeat procedures. It has been shown to be safe, with an adverse event rate ≤1%. This review covers the current indications and yield of CLE and explores avenues required to increase its acceptance into clinical practice.
| Original language | English (US) |
|---|---|
| Title of host publication | ERCP, Third Edition |
| Publisher | Elsevier |
| Pages | 259-262.e1 |
| ISBN (Electronic) | 9780323481090 |
| ISBN (Print) | 9780323527729 |
| DOIs | |
| State | Published - Jan 1 2018 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- General Medicine
Keywords
- advanced imaging
- confocal endomicroscopy
- indeterminate biliary stricture
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