Endophthalmitis

Effectivetreatmentofinfectiousendophthalmitisdepends on early recognition of infection, proper biopsy and culture of material, and proper selection of antibiotics. When, what, and how to biopsy and treat endophthalmitis depends on the clinical setting and findings. The prognosis depends heavily on the culture result (better prognosis if culture negative), the time at onset (better prognosis if late onset, unless associated with trabeculectomy), and the virulence of the pathogen (worst outcomes typically are associated with Streptococcus species, Gram-negative species, and Bacillus species). The classification, physical findings, risk factors, and treatment of endophthalmitis in various clinical settings are considered in detail.