Endoscopic gallbladder drainage compared with percutaneous drainage

Prashant Kedia, Reem Z. Sharaiha, Nikhil A. Kumta, Jessica Widmer, Armeen Jamal-Kabani, Kristen Weaver, Andrea Benvenuto, Jennifer Millman, Rahul Barve, Monica Gaidhane, Michel Kahaleh

Research output: Contribution to journalArticlepeer-review

53 Scopus citations


Background High-risk patients with cholecystitis have conventionally been offered percutaneous gallbladder drainage (PGBD) for treatment. A growing experience of endoscopic gallbladder drainage (EGBD) has been reported to be effective and safe. Objective To compare the short- and long-term outcomes of EGBD and PGBD. Design A retrospective review. Setting Single academic tertiary care center. Patients Inpatients diagnosed with cholecystitis. Interventions Any patient deemed a nonsurgical candidate and who has undergone either PGBD or EGBD was included in the analysis. Main Outcome Measurements Patient demographics along with procedural and clinical outcomes were recorded for each group. Results Forty-three patients underwent PGBD and 30 underwent EGBD (24 transpapillary, 6 transmural). Technical (97.6% vs 100%) and clinical (97.6% vs 86.7%) success rates of PGBD and EGBD were similar. However, postprocedure hospital length of stay (16.3 vs 7.6 days), time to clinical resolution (4.6 vs 3.0 days), adverse event rate (39.5% vs 13.3%), number of sessions (2.0 vs 1.0), number of repeat interventions (53.4% vs 13.3%), and postprocedure pain scores (3.8 vs 2.1) were significantly higher for PGBD than EGBD. Limitations Retrospective analysis. Conclusion Although EGBD has similar technical and clinical success compared with PGBD, it uses fewer hospital resources and results in fewer adverse events, improved pain scores, and decreased need for repeat gallbladder drainage. EGBD may provide a less-invasive, safer, cost-effective option for gallbladder drainage than PGBD with improved clinical outcomes.

Original languageEnglish (US)
Pages (from-to)1031-1036
Number of pages6
JournalGastrointestinal Endoscopy
Issue number6
StatePublished - Dec 1 2015

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology


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