@article{4d89428a4ac6478ca424c79e20e54ccb,
title = "Enhanced relative biological effectiveness of proton radiotherapy in tumor cells with internalized gold nanoparticles",
abstract = "The development and use of sensitizing agents to improve the effectiveness of radiotherapy have long been sought to improve our ability to treat cancer. In this letter, we have studied the relative biological effectiveness of proton beam radiotherapy on prostate tumor cells with and without internalized gold nanoparticles. The effectiveness of proton radiotherapy for the killing of prostate tumor cells was increased by approximately 15%-20% for those cells containing internalized gold nanoparticles.",
author = "Polf, {Jerimy C.} and Bronk, {Lawrence F.} and Driessen, {Wouter H.P.} and Wadih Arap and Renata Pasqualini and Michael Gillin",
note = "Funding Information: This work was supported by awards from the Gillson-Longenbaugh Foundation, AngelWorks, and the Marcus Foundation (to R. Pasqualini and W. Arap). Conflict of Interest Disclosure: The University of Texas and authors W. Arap and R. Pasqualini have equity in Ablaris Therapeutics and Mercator Therapeutics, which is subjected to certain restrictions under university policy; the university manages and monitors the terms of these arrangements in accordance to its conflict of interest policy.",
year = "2011",
month = may,
day = "9",
doi = "10.1063/1.3589914",
language = "English (US)",
volume = "98",
journal = "Applied Physics Letters",
issn = "0003-6951",
publisher = "American Institute of Physics Publising LLC",
number = "19",
}