Enterovirus a71 vaccines

Mei Ling Li; Shin Ru Shih; Blanton S. Tolbert; Gary Brewer

doi:10.3390/vaccines9030199

Enterovirus a71 vaccines

Mei Ling Li, Shin Ru Shih, Blanton S. Tolbert, Gary Brewer

Research output: Contribution to journal › Review article › peer-review

23 Scopus citations

Abstract

Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease (HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications and death. Vaccination is the most efficient way to control virus infection. There are currently three inactivated, whole EV-A71 vaccines licensed by the China NMPA (National Medical Products Administration). Several other types of vaccines, such as virus-like particles and recombinant VP1 (capsid protein), are also under development. In this review, we discuss recent advances in the development of EV-A71 vaccines.

Original language	English (US)
Article number	199
Pages (from-to)	1-10
Number of pages	10
Journal	Vaccines
Volume	9
Issue number	3
DOIs	https://doi.org/10.3390/vaccines9030199
State	Published - 2021

All Science Journal Classification (ASJC) codes

Immunology
Pharmacology
Drug Discovery
Infectious Diseases
Pharmacology (medical)

Keywords

Enterovirus A71
Foot and mouth disease (HFMD)
Hand
Sinovac
Vaccine

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10.3390/vaccines9030199

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title = "Enterovirus a71 vaccines",

abstract = "Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease (HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications and death. Vaccination is the most efficient way to control virus infection. There are currently three inactivated, whole EV-A71 vaccines licensed by the China NMPA (National Medical Products Administration). Several other types of vaccines, such as virus-like particles and recombinant VP1 (capsid protein), are also under development. In this review, we discuss recent advances in the development of EV-A71 vaccines.",

keywords = "Enterovirus A71, Foot and mouth disease (HFMD), Hand, Sinovac, Vaccine",

author = "Li, {Mei Ling} and Shih, {Shin Ru} and Tolbert, {Blanton S.} and Gary Brewer",

note = "Funding Information: Funding: This work was funded by National Institutes of Health R01 GM126833 to B.S.T. and G.B., and by the Research Center for Emerging Viral Infections from The Featured Areas Research Center Program within the framework of the Higher Education Sprout Project by the Ministry of Education in Taiwan and the Ministry of Science and Technology, Taiwan (MOST 108–3017-F−182–001) to S.R.S. Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2021",

doi = "10.3390/vaccines9030199",

language = "English (US)",

volume = "9",

pages = "1--10",

journal = "Vaccines",

issn = "2076-393X",

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T1 - Enterovirus a71 vaccines

AU - Li, Mei Ling

AU - Shih, Shin Ru

AU - Tolbert, Blanton S.

AU - Brewer, Gary

N1 - Funding Information: Funding: This work was funded by National Institutes of Health R01 GM126833 to B.S.T. and G.B., and by the Research Center for Emerging Viral Infections from The Featured Areas Research Center Program within the framework of the Higher Education Sprout Project by the Ministry of Education in Taiwan and the Ministry of Science and Technology, Taiwan (MOST 108–3017-F−182–001) to S.R.S. Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2021

Y1 - 2021

N2 - Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease (HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications and death. Vaccination is the most efficient way to control virus infection. There are currently three inactivated, whole EV-A71 vaccines licensed by the China NMPA (National Medical Products Administration). Several other types of vaccines, such as virus-like particles and recombinant VP1 (capsid protein), are also under development. In this review, we discuss recent advances in the development of EV-A71 vaccines.

AB - Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease (HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications and death. Vaccination is the most efficient way to control virus infection. There are currently three inactivated, whole EV-A71 vaccines licensed by the China NMPA (National Medical Products Administration). Several other types of vaccines, such as virus-like particles and recombinant VP1 (capsid protein), are also under development. In this review, we discuss recent advances in the development of EV-A71 vaccines.

KW - Enterovirus A71

KW - Foot and mouth disease (HFMD)

KW - Hand

KW - Sinovac

KW - Vaccine

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U2 - 10.3390/vaccines9030199

DO - 10.3390/vaccines9030199

M3 - Review article

AN - SCOPUS:85102712550

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VL - 9

SP - 1

EP - 10

JO - Vaccines

JF - Vaccines

IS - 3

M1 - 199

ER -

Enterovirus a71 vaccines

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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