Enterovirus a71 vaccines

Mei Ling Li, Shin Ru Shih, Blanton S. Tolbert, Gary Brewer

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease (HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications and death. Vaccination is the most efficient way to control virus infection. There are currently three inactivated, whole EV-A71 vaccines licensed by the China NMPA (National Medical Products Administration). Several other types of vaccines, such as virus-like particles and recombinant VP1 (capsid protein), are also under development. In this review, we discuss recent advances in the development of EV-A71 vaccines.

Original languageEnglish (US)
Article number199
Pages (from-to)1-10
Number of pages10
JournalVaccines
Volume9
Issue number3
DOIs
StatePublished - 2021

All Science Journal Classification (ASJC) codes

  • Immunology
  • Pharmacology
  • Drug Discovery
  • Infectious Diseases
  • Pharmacology (medical)

Keywords

  • Enterovirus A71
  • Foot and mouth disease (HFMD)
  • Hand
  • Sinovac
  • Vaccine

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