Abstract

In this issue, Overholtzer et al. (2007) describe a new nonapoptotic cell death pathway termed "entosis" in mammary epithelial cells that have detached from the extracellular matrix (ECM). Given that surviving detachment from the ECM is an event associated with the progression of epithelial cancers, entosis-along with apoptosis-may contribute to tumor suppression by promoting the elimination of cancer cells.

Original languageEnglish (US)
Pages (from-to)840-842
Number of pages3
JournalCell
Volume131
Issue number5
DOIs
StatePublished - Nov 30 2007

All Science Journal Classification (ASJC) codes

  • General Biochemistry, Genetics and Molecular Biology

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