Environmental effect on a thermoplastic elastomer (TPE) for use in a composite intervertebral disc spacer

Monica Vuono Hawkins, Mark C. Zimmerman, J. Russell Parsons, Noshir A. Langrana, Casey K. Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Four durometers of a modified copolymer of styrene-ethylene/butylene-styrene were evaluated after in-vitro exposure to saline at 37°C (3, 6, 9, or 12 months) or in-vivo subcutaneous implantation (3 months). Specimens were evaluated for changes in mass, chemistry, and mechanical behavior. In-vitro exposure resulted in minimal moisture uptake by all durometers, no chemical alterations in any durometer, and slightly increased stiffness of the 90A durometer. All changes occurred within the first three months. In-vivo exposure resulted in a greater increase in mass, particularly of the 70A durometer. Chemical alteration in the form of an exaggerated carbonyl was observed in the 70A durometer only. These changes are indicative of possible lipid absorption. Mechanical changes included decreased stiffness of the 35A and 50A durometers, increased stiffness of the 90A durometer, and no change in the 70A durometer. These changes do not reflect the physical and chemical changes and are attributed to a balance between lipid and fluid absorption along with possible absorption of biological antiplasticizing agents or mineral oil leaching, or both.

Original languageEnglish (US)
Title of host publicationASTM Special Technical Publication
PublisherPubl by ASTM
Pages17-26
Number of pages10
Edition1178
ISBN (Print)080311852X
StatePublished - 1993
Externally publishedYes
EventComposite Materials for Implant Applications in the Human Body; Characterization and Testing - San Diego, CA, USA
Duration: Nov 6 1991Nov 6 1991

Publication series

NameASTM Special Technical Publication
Number1178
ISSN (Print)0066-0558

Other

OtherComposite Materials for Implant Applications in the Human Body; Characterization and Testing
CitySan Diego, CA, USA
Period11/6/9111/6/91

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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