@article{75ee5471c5644d4ba6e3fc33549e1126,
title = "Environmental enrichment with nesting material accelerates wound healing in isolation-reared rats",
abstract = "Early enrichment (EE) programs provide a well-established approach to mitigate the deleterious effects of childhood adversity. To better understand the therapeutic features of EE, in the current study we compared the effect of two forms of nesting material on isolation reared (IR) rats. We found that both materials, absent of social and any other physical enrichment, significantly improved wound healing rates. The results suggest that this animal model may provide useful insights into the critical components of EE.",
keywords = "Bedding, Environmental enrichment, Isolation rearing, Nesting, Wound healing",
author = "Vitalo, {Antonia G.} and Sasikanth Gorantla and Fricchione, {Jonathan G.} and Scichilone, {John M.} and Jennifer Camacho and Niemi, {Steven M.} and Denninger, {John W.} and Herbert Benson and Yarmush, {Martin L.} and Levine, {John B.}",
note = "Funding Information: Funding for this study was provided by the John Henry Foundation , the Benson-Henry Institute (BHI) for Mind Body Medicine at Massachusetts GeneralHospital , and the Medical Research Programs of the Shriners Burns Hospital for Children – Boston. The John-Henry Foundation provides research funding to the BHI. One of the authors, Herbert Benson, MD, is Principal Investigator on the John Henry Foundation Fund at BHI. The John Henry Foundation itself had no role in study design, data collection, analysis, or decision to publish, or in preparation of the manuscript. The authors acknowledge the help of Mr. Don Poulsen in preparing the figures. ",
year = "2012",
month = jan,
day = "15",
doi = "10.1016/j.bbr.2011.09.038",
language = "English (US)",
volume = "226",
pages = "606--612",
journal = "Behavioural Brain Research",
issn = "0166-4328",
publisher = "Elsevier",
number = "2",
}