Epithelioid leiomyosarcoma of the ovary

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Introduction. Leiomyosarcoma of the ovary is a rare lesion usually seen in postmenopausal women. Epithelioid leiomyosarcoma of the ovary is exceptionally rare, with only one previously reported case. Case. A 42-year-old nulliparous woman undergoing ovulation induction presented with a left adnexal mass. An exploratory laparotomy was performed. Frozen section diagnosis was read as fibrothecoma, and an oophorectomy was performed. The final diagnosis was epithelioid leiomyosarcoma of the ovary. Subsequently, a staging procedure including hysterectomy was performed with no residual disease. Discussion. This is an unusual case for several reasons. Most leiomyosarcomas of the ovary have occurred in postmenopausal women and were of advanced stage at diagnosis. Our case had an epithelioid histology, occurred in a premenopausal woman, and was confined to the ovary. The fact that the patient was undergoing ovulation induction at the time of diagnosis raises the question of the risk of developing ovarian neoplasms with these medications.

Original languageEnglish (US)
Pages (from-to)697-699
Number of pages3
JournalGynecologic Oncology
Issue number2
StatePublished - May 2005

All Science Journal Classification (ASJC) codes

  • Oncology
  • Obstetrics and Gynecology


  • Epithelioid leiomyosarcoma
  • Ovary
  • Premenopausal women


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