Ethics guidelines for research with the recently dead

Rebecca D. Pentz; Cynthia B. Cohen; Mark Wicclair; Michael A. DeVita; Anne Lederman Flamm; Stuart J. Youngner; Ann B. Hamric; Mary S. McCabe; Jacqueline J. Glover; Winona J. Kittiko; Kathy Kinlaw; James Keller; Adrienne Asch; John J. Kavanagh; Wadih Arap

doi:10.1038/nm1105-1145

Ethics guidelines for research with the recently dead

Rebecca D. Pentz, Cynthia B. Cohen, Mark Wicclair, Michael A. DeVita, Anne Lederman Flamm, Stuart J. Youngner, Ann B. Hamric, Mary S. McCabe, Jacqueline J. Glover, Winona J. Kittiko, Kathy Kinlaw, James Keller, Adrienne Asch, John J. Kavanagh, Wadih Arap

Research output: Contribution to journal › Review article › peer-review

71 Scopus citations

Abstract

The objective of the multidisciplinary expert Consensus Panel on Research with the Recently Dead (CPRRD) was to craft ethics guidelines for research with the recently dead. The CPRRD recommends that research with the recently dead: (i) receive scientific and ethical review and oversight; (ii) involve the community of potential research subjects; (iii) be coordinated with organ procurement organizations; (iv) not conflict with organ donation or required autopsy; (v) use procedures respectful of the dead; (vi) be restricted to one procedure per day; (vii) preferably be authorized by first-person consent, though both general advance research directives and surrogate consent are acceptable; (viii) protect confidentiality; (ix) not impose costs on subjects' estates or next of kin and not involve payment; (x) clearly explain ultimate disposition of the body.

Original language	English (US)
Pages (from-to)	1145-1149
Number of pages	5
Journal	Nature medicine
Volume	11
Issue number	11
DOIs	https://doi.org/10.1038/nm1105-1145
State	Published - Nov 2005
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry, Genetics and Molecular Biology(all)

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10.1038/nm1105-1145

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title = "Ethics guidelines for research with the recently dead",

abstract = "The objective of the multidisciplinary expert Consensus Panel on Research with the Recently Dead (CPRRD) was to craft ethics guidelines for research with the recently dead. The CPRRD recommends that research with the recently dead: (i) receive scientific and ethical review and oversight; (ii) involve the community of potential research subjects; (iii) be coordinated with organ procurement organizations; (iv) not conflict with organ donation or required autopsy; (v) use procedures respectful of the dead; (vi) be restricted to one procedure per day; (vii) preferably be authorized by first-person consent, though both general advance research directives and surrogate consent are acceptable; (viii) protect confidentiality; (ix) not impose costs on subjects' estates or next of kin and not involve payment; (x) clearly explain ultimate disposition of the body.",

author = "Pentz, {Rebecca D.} and Cohen, {Cynthia B.} and Mark Wicclair and DeVita, {Michael A.} and Flamm, {Anne Lederman} and Youngner, {Stuart J.} and Hamric, {Ann B.} and McCabe, {Mary S.} and Glover, {Jacqueline J.} and Kittiko, {Winona J.} and Kathy Kinlaw and James Keller and Adrienne Asch and Kavanagh, {John J.} and Wadih Arap",

note = "Funding Information: We thank J. Menikoff, E.P. Richards, R.S. Shapiro and R.Veatch for advising us on the UAGA requirements and OPO practices. We also thank I. Stith-Coleman for her participation as a resource consultant to the panel, and B. Kilburn for preparing notes of the conference. The final guidelines are solely the responsibility of the CPRRD. The CPRRD was supported by grants from the University of Pittsburgh Medical Center and Health System, Emory Office of Research, the National Cancer Institute 1R13CA108423 and William A. Parker, Jr. All authors were members of the CPRRD and participated fully in the drafting and editing of the recommendations.",

year = "2005",

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doi = "10.1038/nm1105-1145",

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AU - Pentz, Rebecca D.

AU - Cohen, Cynthia B.

AU - Wicclair, Mark

AU - DeVita, Michael A.

AU - Flamm, Anne Lederman

AU - Youngner, Stuart J.

AU - Hamric, Ann B.

AU - McCabe, Mary S.

AU - Glover, Jacqueline J.

AU - Kittiko, Winona J.

AU - Kinlaw, Kathy

AU - Keller, James

AU - Asch, Adrienne

AU - Kavanagh, John J.

AU - Arap, Wadih

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Ethics guidelines for research with the recently dead

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