Evaluation of fetal lungs and stomach in the determination of amniotic sac infection

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This study evaluated neutrophils in fetal lung/stomach, in association with chorioamnionitis. Reports/slides from fetuses 1324 weeks with a confirmed histologic diagnosis of placental chorioamnionitis were reviewed. There were 94 cases with no neutrophils in the lungs or stomach, and 106 with neutrophils in lungs, stomach, or both (53%). Thirteen percent showed neutrophils in the lungs only. Fetuses with no neutrophils were older than those with neutrophils in the stomach only (p = 0.008). Neutrophils in fetal lungs/stomach are common, and may confirm chorioamnionitis when the placenta is not available. Submission of gastric sections increases identification of chorioamnionitis.

Original languageEnglish (US)
Pages (from-to)394-396
Number of pages3
JournalFetal and Pediatric Pathology
Issue number6
StatePublished - Nov 10 2011

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine


  • Chorioamnionitis
  • Fetus
  • Placenta


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