This study evaluated neutrophils in fetal lung/stomach, in association with chorioamnionitis. Reports/slides from fetuses 1324 weeks with a confirmed histologic diagnosis of placental chorioamnionitis were reviewed. There were 94 cases with no neutrophils in the lungs or stomach, and 106 with neutrophils in lungs, stomach, or both (53%). Thirteen percent showed neutrophils in the lungs only. Fetuses with no neutrophils were older than those with neutrophils in the stomach only (p = 0.008). Neutrophils in fetal lungs/stomach are common, and may confirm chorioamnionitis when the placenta is not available. Submission of gastric sections increases identification of chorioamnionitis.
All Science Journal Classification (ASJC) codes
- Pediatrics, Perinatology, and Child Health
- Pathology and Forensic Medicine