Evidence for the coexistence of glutamate decarboxylase and Met-enkephalin immunoreactivities in axon terminals of rat ventral pallidum

D. S. Zahm, L. Zaborszky, V. E. Alones, L. Heimer

Research output: Contribution to journalArticlepeer-review

171 Scopus citations

Abstract

Evidence for the coexistence of glutamate decarboxylase (GAD) and Met-enkephalin (Met-Enk) in axon terminals of ventral pallidum was demonstrated by colocalization of anti-GAD and anti-Met-Enk immunoreactivities in alternate adjacent 1 μm serial sections. Conventional electron microscopy of immunostained ventral pallidum confirmed that the immunoreactive structures were boutons which made predominantly symmetrical synapses on ventral pallidal cell bodies and dendrites.

Original languageEnglish (US)
Pages (from-to)317-321
Number of pages5
JournalBrain research
Volume325
Issue number1-2
DOIs
StatePublished - Jan 28 1985
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Keywords

  • Met-Enkephalin
  • axon terminals
  • coexistence
  • glutamate decarboxylase
  • immunoreactivity
  • substance P
  • ventral pallidum

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