Evidence for the Presence of a Ganglioside Transfer Protein in Brain

CM Gammon; R. W. Ledeen

doi:10.1111/j.1471-4159.1985.tb12912.x

Evidence for the Presence of a Ganglioside Transfer Protein in Brain

CM Gammon, R. W. Ledeen

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Abstract: An extract from rat brain has been shown to catalyze the transfer of ganglioside G_M1 from sonicated vesicles to erythrocyte ghosts. It also enhanced the transfer of G_M1 to a crude neuronal membrane preparation, whereas myelin took up only a very limited amount. The transfer activity was heat‐labile. Similar transfer activities were found in extracts from bovine gray and white matter, that of the former being comparable to rat brain whereas the latter was greater per milligram protein.

Original language	English (US)
Pages (from-to)	979-982
Number of pages	4
Journal	Journal of neurochemistry
Volume	44
Issue number	3
DOIs	https://doi.org/10.1111/j.1471-4159.1985.tb12912.x
State	Published - Mar 1985
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Cellular and Molecular Neuroscience

Keywords

Ganglioside transfer protein
Gangliosides
Myelin
Neuronal membranes
Red cell membranes

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10.1111/j.1471-4159.1985.tb12912.x

Cite this

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abstract = "Abstract: An extract from rat brain has been shown to catalyze the transfer of ganglioside GM1 from sonicated vesicles to erythrocyte ghosts. It also enhanced the transfer of GM1 to a crude neuronal membrane preparation, whereas myelin took up only a very limited amount. The transfer activity was heat‐labile. Similar transfer activities were found in extracts from bovine gray and white matter, that of the former being comparable to rat brain whereas the latter was greater per milligram protein.",

keywords = "Ganglioside transfer protein, Gangliosides, Myelin, Neuronal membranes, Red cell membranes",

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year = "1985",

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AU - Ledeen, R. W.

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AB - Abstract: An extract from rat brain has been shown to catalyze the transfer of ganglioside GM1 from sonicated vesicles to erythrocyte ghosts. It also enhanced the transfer of GM1 to a crude neuronal membrane preparation, whereas myelin took up only a very limited amount. The transfer activity was heat‐labile. Similar transfer activities were found in extracts from bovine gray and white matter, that of the former being comparable to rat brain whereas the latter was greater per milligram protein.

KW - Ganglioside transfer protein

KW - Gangliosides

KW - Myelin

KW - Neuronal membranes

KW - Red cell membranes

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ER -

Evidence for the Presence of a Ganglioside Transfer Protein in Brain

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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