Evidence for the Presence of a Ganglioside Transfer Protein in Brain

CM Gammon, R. W. Ledeen

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Abstract: An extract from rat brain has been shown to catalyze the transfer of ganglioside GM1 from sonicated vesicles to erythrocyte ghosts. It also enhanced the transfer of GM1 to a crude neuronal membrane preparation, whereas myelin took up only a very limited amount. The transfer activity was heat‐labile. Similar transfer activities were found in extracts from bovine gray and white matter, that of the former being comparable to rat brain whereas the latter was greater per milligram protein.

Original languageEnglish (US)
Pages (from-to)979-982
Number of pages4
JournalJournal of neurochemistry
Volume44
Issue number3
DOIs
StatePublished - Mar 1985
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Cellular and Molecular Neuroscience

Keywords

  • Ganglioside transfer protein
  • Gangliosides
  • Myelin
  • Neuronal membranes
  • Red cell membranes

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