Exceedingly Sensitive Restructured Electrodes Design for Pathogen Morphology Detection using Impedance Flow Cytometry

Amina Farooq, Nauman Z. Butt, Umer Hassan

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

The cellular morphology is a vital biological characteristic for determining explicit information about its physiological state. Monitoring real-time cell shape is of great importance in infectious pathogen detection. Here, we designed a highly sensitive coplanar electrode sensing system and merged it with planar electrodes for simultaneous impedance signals in two dimensions. We simulated the proposed design in this study for the detection of different single cell pathogens based on their morphology. The optimized design has a great potential to monitor and characterize different bacteria based on their sizes and shapes. In this report, spherical and rod shaped particles were used to illustrate the device performance. This simple and extremely sensitive modified electrode design is very promising for bacterial detection and will serve as a future guiding tool for discriminating different morphologies of singular cells.

Original languageEnglish (US)
Title of host publication42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publicationEnabling Innovative Technologies for Global Healthcare, EMBC 2020
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages2500-2503
Number of pages4
ISBN (Electronic)9781728119908
DOIs
StatePublished - Jul 2020
Event42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC 2020 - Montreal, Canada
Duration: Jul 20 2020Jul 24 2020

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume2020-July
ISSN (Print)1557-170X

Conference

Conference42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC 2020
Country/TerritoryCanada
CityMontreal
Period7/20/207/24/20

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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