Exercise training-induced hypervolemia in greyhounds: Role of water intake and renal mechanisms

Kenneth McKeever, W. A. Schurg, V. A. Convertino

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Abstract

The purpose of this study was to determine if the chronic hypervolemia that accompanies endurance exercise training is due only to an increase in the rate of water intake or if there were contributions from renal mechanisms. Four greyhound dogs, previously sedentary for 3 yr, were utilized. During the 28-day experiment each dog was trained on a treadmill ergometer for 14 consecutive days at 65% of its pretraining maximal work intensity. After training, plasma volume increased 472 ml (27.5%, P < 0.05). The rate of water intake increased 328 ml/day (33%, P < 0.05), whereas urine output increased 87 ml/day (20.8% P < 0.05). The mean resting 24-h values for clearance of sodium increased 0.29 ml/min (90.3%, P < 0.05), and clearance of potassium decreased 1.51 ml/min (16.1%, NS). Glomerular filtration rate, free water clearance, and osmotic clearance were not significantly altered. These data suggest that the primary mechanism for the exercise training-induced hypervolemia in dogs is a net positive water balance via increased water consumption without significant contribution from an increase in renal water reabsorption.

Original languageEnglish (US)
JournalAmerican Journal of Physiology - Regulatory Integrative and Comparative Physiology
Volume17
Issue number4
StatePublished - Jan 1 1985
Externally publishedYes

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Drinking
Dogs
Exercise
Kidney
Water
Plasma Volume
Glomerular Filtration Rate
Potassium
Sodium
Urine
Renal Reabsorption

All Science Journal Classification (ASJC) codes

  • Physiology
  • Physiology (medical)

Cite this

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abstract = "The purpose of this study was to determine if the chronic hypervolemia that accompanies endurance exercise training is due only to an increase in the rate of water intake or if there were contributions from renal mechanisms. Four greyhound dogs, previously sedentary for 3 yr, were utilized. During the 28-day experiment each dog was trained on a treadmill ergometer for 14 consecutive days at 65{\%} of its pretraining maximal work intensity. After training, plasma volume increased 472 ml (27.5{\%}, P < 0.05). The rate of water intake increased 328 ml/day (33{\%}, P < 0.05), whereas urine output increased 87 ml/day (20.8{\%} P < 0.05). The mean resting 24-h values for clearance of sodium increased 0.29 ml/min (90.3{\%}, P < 0.05), and clearance of potassium decreased 1.51 ml/min (16.1{\%}, NS). Glomerular filtration rate, free water clearance, and osmotic clearance were not significantly altered. These data suggest that the primary mechanism for the exercise training-induced hypervolemia in dogs is a net positive water balance via increased water consumption without significant contribution from an increase in renal water reabsorption.",
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