Expanding human mesenchymal stem cells from the umbilical cord

Lauren S. Sherman, Andrew Petryna, Matthew P. Romagano, Pranela Rameshwar

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Umbilical cord (UC) is considered a discarded tissue. However, this cord is a "rich" source of mesenchymal stem cells (UC-MSCs). As compared to other sources from adipose and bone marrow, the UC has reduced ethical concern. Despite the ease of obtaining UC, you are most likely to require an approved informed consent by the mother. This chapter provides a stepwise procedure, adapted from a method provided by Dr. Francesco Dazzi. The technique describes the method to expand UC-MSCs from UC. Thus, UC-MSCs might not be able to replace similar cells from other sources. Thus, investigators will be required to determine the application in experimental studies.

Original languageEnglish (US)
Title of host publicationStepwise Culture of Human Adult Stem Cells
PublisherRiver Publishers
Pages69-74
Number of pages6
ISBN (Electronic)9788770228893
ISBN (Print)9788770228541
StatePublished - Oct 30 2023
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Computer Science
  • General Economics, Econometrics and Finance
  • General Business, Management and Accounting

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