Experimental and theoretical evidence supporting the role of Gly³⁶³ in blood coagulation factor IXa (Gly¹⁹³ in Chymotrypsin) for proper activation of the proenzyme

Keyphrases

• Factor IXa 100%
• Chymotrypsin 100%
• Blood Coagulation Factors 100%
• Proenzymes 100%
• Factor 9 60%
• Ca2+ 40%
• Substrate Binding Site 40%
• Catalytic Domain 40%
• Serine Protease 40%
• Oxyanion Hole 40%
• Factor VIIIa 40%
• Polymerase Chain Reaction Assay 20%
• Monoclonal Antibody 20%
• Carbohydrate Content 20%
• Phospholipids 20%
• Active Sites 20%
• Active Conformation 20%
• Binding Region 20%
• Structural Information 20%
• X-ray Crystallography 20%
• Specific Inhibitor 20%
• Single-point mutation 20%
• Gel Electrophoresis 20%
• Isoelectric Point 20%
• Variant Proteins 20%
• Urea 20%
• Exon 20%
• Blood Coagulation 20%
• Crystallographic Data 20%
• Aspartic Acid 20%
• Trypsin 20%
• Zymogen 20%
• Acid Content 20%
• Biologic Activity 20%
• Acid Residue 20%
• Sodium Dodecyl Sulfate 20%
• Antithrombin III (ATIII) 20%
• Protease Family 20%
• Hemophilia B 20%
• Factor Interaction 20%
• Active Site Conformation 20%
• Carbohydrate Allocation 20%
• Factor XIa 20%

Biochemistry, Genetics and Molecular Biology

• Chymotrypsin 100%
• Blood Coagulation Factor 100%
• Factor IX 75%
• Binding Site 50%
• Conformation 50%
• Active Site 50%
• Enzyme Active Site 50%
• Serine Protease 50%
• Oxyanion Hole 50%
• Enzyme 25%
• Monoclonal Antibody 25%
• X Ray 25%
• Point Mutation 25%
• Coagulation System 25%
• Exon 25%
• Zymogen 25%
• Sodium Dodecyl Sulfate 25%
• Antithrombin 25%
• Carboxyglutamic Acid 25%
• Haemophilia B 25%
• Aspartic Acid 25%
• Polymerase Chain Reaction 25%
• Phospholipid 25%
• Gel Electrophoresis 25%
• Isoelectric Point 25%
• Factor X 25%